Interaction of ibogaine analogs with the nicotinic acetylcholine receptor
The FASEB Journal April 1, 2008 Krzysztof Jozwiak, Ruin Moaddel, Irving W. Wainer et al. 2 citations
PURPOSE: Characterization of the binding sites for ibogaine analogs on the nicotinic acetylcholine receptor (AChR) in the resting and desensitized states. METHODS: [ 3 H]18‐methoxycoronaridine ([ 3 H]18‐MC) Scatchard‐plots using Torpedo AChR membranes, [ 3 H]TCP (a well characterized noncompetitive antagonist) competition binding experiments and Schild‐type analysis, analog‐induced binding...