Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat
European Journal of Pharmacology October 1, 1985 Mark D. Tricklebank, Christian Forler, Derek N. Middlemiss et al. 141 citations
The 5-HT receptor subtypes involved in the mediation of reciprocal forepaw treading and the flat body posture induced by the central 5-HT receptor agonist, 5-methoxy-N,N-dimethyltryptamine (5-MeODMT), were examined in intact rats and in rats depleted of monoamines with reserpine. Forepaw treading in non-reserpinised rats was antagonised by the 5-HT2 receptor antagonist, ketanserin, only at...
DOI: 10.1016/0014-2999(85)90467-4 (opens in new tab)
Serotonin
Ketanserin
Pindolol
Agonist
+8