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Miryam Sperka

2 papers in the library · 3 citations · publishing 2026

Papers

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Balancing Innovation and Evidence: Reflections on Structured Protocols in MDMA-Assisted Therapy Versus a Principle-Guided, Patient-Directed Approach

Psychedelic Medicine March 10, 2026 Amy Lehrner, Miryam Sperka, Lauren Lepow et al. 1 citation

There is growing interest in incorporating MDMA (3,4-Methylenedioxymethamphetamine) into structured, evidence-based cognitive-behavioral treatment protocols for post-traumatic stress disorder. Yet this risks overlooking the distinctive qualities of MDMA-assisted therapy, which has already demonstrated strong clinical effects, high response rates, and low dropout using a principle-guided,...

The case for an integrative model: Hypotheses and rationale for integrative MDMA-Assisted Psychotherapy (IMAP)

Psychedelics January 8, 2026 Rachel Yehuda, Amy Lehrner, Miryam Sperka et al. 2 citations

The original MAPS manual for MDMA-assisted therapy (MDMA-AT) opened a therapeutic frontier for PTSD. However, it drew critique for concepts—such as “inner healing intelligence” – that originated in transpersonal traditions rather than academic or empirically grounded clinical models. While many patients found the therapies helpful, these constructs were difficult to interpret and standardize....