Autism Spectrum Disorder (ASD) is a neurodevelopmental condition marked by persistent social communication deficits and repetitive behaviors, with communication abilities ranging from nonverbal to verbally fluent yet socially impaired. These deficits, linked to disrupted neural connectivity in regions like the posterior superior temporal sulcus (pSTS), reward circuits, and dorsal/ventral speech...
Background: Treatment-resistant depression (TRD) affects up to a third of patients with major depressive disorder and remains difficult to manage with conventional therapies. Rapid-acting antidepressants targeting the glutamatergic system, such as ketamine, esketamine, and dextromethorphan-bupropion, have emerged as promising alternatives. Nitrous oxide, also an NMDA receptor antagonist, has...
Complex regional pain syndrome (CRPS) is a chronic pain disorder that severely affects mobility and quality of life. This case report describes an 86-year-old man who has a long-standing history of CRPS-related back and leg pain. Traditional treatments, including opioids and duloxetine, did not improve his symptoms, and due to religious beliefs restricting specific interventions, standard...