Mental health outcomes following a psilocybin session within Oregon’s state-regulated model: A naturalistic study
medRxiv February 19, 2026 Amanda Gow, Emily Shih, Ryan Reid et al.
Abstract Background In 2020, Oregon became the first U.S. state to establish a regulated framework for adults to access psilocybin services using naturally-derived mushroom products. No studies have examined mental health outcomes among individuals receiving psilocybin in this context. Aims To evaluate changes in self-reported symptoms of depression, anxiety, and well-being 30-days...