Real-world use, safety, and mental health efficacy of regulated psilocybin services in Oregon and Colorado
medRxiv August 12, 2026 Scott M. Thompson, Devin P. Effinger, Andrew M Novick et al. preprint
Abstract Oregon (OR) and Colorado (CO) were the first states to enact regulations for provision of psilocybin with support of licensed ‘facilitators.’ As more states and countries adopt similar policies, informed public policy decisions require that client characteristics and rationale for using psilocybin, psilocybin dosing practices, mental health outcomes, and adverse events are understood....