John Swygert

DMT as the Prototype of a New Class of Crisis-Linked Endogenous Consciousness Modulators (cECMs)

Zenodo (CERN European Organization for Nuclear Research) November 23, 2025 John Swygert preprint

DescriptionThis preprint proposes a new biological classification for N,N-dimethyltryptamine (DMT): crisis-linked endogenous consciousness modulators (cECMs). Using six mechanistically grounded, falsifiable criteria—endogenous neural biosynthesis, deep evolutionary conservation, ultra-rapid pharmacokinetics, multi-receptor promiscuity, crisis-linked release, and induction of information-rich...