Lysergic acid diethylamide (LSD) has shown remarkable potential in modulating brain functional organization and dynamics. However, the exact mechanisms underlying its effects remain unclear. In this study, we employed a data-driven approach to analyze recurrent functional connectivity patterns in resting-state fMRI data and developed a parameterized feedback inhibition model to characterize...
Currently, treatment options for patients with treatment-resistant depression (TRD) are extremely limited. Although the rapid antidepressant effects of nitrous oxide have been preliminarily validated, the underlying neurophysiological mechanisms remain unclear. In this study, we intended to explore impact on brain modules induced by nitrous oxide through a randomized controlled study. A total...