Skip to content

Thomas A. Smith

2 papers in the library · 4 citations · publishing 2025

Papers

Sort Most recent Most cited

Participant Experiences of Microdosed Lysergic Acid Diethylamide in a 6-Week Randomised Controlled Trial

Journal of Humanistic Psychology November 10, 2025 Robin J Murphy, Mia Wardlaw, Thomas A. Smith et al.

Microdosing psychedelics is an increasingly popular phenomenon where small amounts of psychedelic drugs are taken regularly. Qualitative data have been published regarding the experiences of microdosers, but never in the context of a randomised controlled trial. Semi-structured video interviews with 40 healthy males were conducted following a double-blind placebo-controlled trial of 10 µg of...

LSD microdosing in major depressive disorder: results from an open-label trial

Neuropharmacology November 5, 2025 Dimitri Daldegan-Bueno, C Donegan, Rachael Sumner et al. 4 citations

Major depressive disorder (MDD) affects approximately 5 % of the global population. Classic psychedelics have shown promise in treating various mental health disorders. This study evaluated the feasibility and tolerability of an 8-week regimen of microdosed lysergic acid diethylamide (LSD) as a treatment for major depressive disorder in an open-label phase 2A trial (LSDDEP1). Nineteen...