Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression.
Frontiers in Pharmacology 2025 Sarah Delcourte, Amel Bouloufa, Renaud Rovera et al. 3 citations
Beside image vision, light plays a pivotal role in regulating diverse non-visual functions, including affective behaviors. Recently, bright light stimulation (BLS) was revealed to be beneficial for treating non-seasonal depression, although its mechanism of action is not fully understood. We developed a novel mouse model of refractory depression, induced through social isolation and chronic...
DOI: 10.3389/fphar.2025.1592909 (opens in new tab)
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Ketamine
Treatment-resistant depression
Animal model
Bright light stimulation
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