Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression.
Frontiers in Pharmacology 2025 Sarah Delcourte, Amel Bouloufa, Renaud Rovera et al. 3 citations
Beside image vision, light plays a pivotal role in regulating diverse non-visual functions, including affective behaviors. Recently, bright light stimulation (BLS) was revealed to be beneficial for treating non-seasonal depression, although its mechanism of action is not fully understood. We developed a novel mouse model of refractory depression, induced through social isolation and chronic...