Psilocybin Prolongs the Neurovascular Coupling Response in Mouse Visual Cortex
bioRxiv (Cold Spring Harbor Laboratory) July 31, 2025 Rick Zirkel, Matthew Isaacson, Clara Liao et al. 3 citations preprint
Abstract Psilocybin has profound therapeutic potential for various mental health disorders, but its mechanisms of action are unknown. Functional MRI studies have reported the effects of psilocybin on brain activity and connectivity; however, these measurements rely on neurovascular coupling to infer neural activity changes and assume that blood flow responses to neural activity are not altered...