Neurorestorative Properties of Ibogaine: Linking Multi-Receptor Affinities to Remyelination and Metabolic Restoration
Acta Neuropsychiatrica February 13, 2026 Tanya Calvey, Demi Govender, Gavin Owen et al.
Ibogaine is a psychedelic alkaloid without an approved indication. Observational clinical research shows linkages between single administration of ibogaine and relief of symptoms of neuropsychiatric conditions including substance use disorder, multiple sclerosis, and traumatic brain injury. Ibogaine has multi-receptor actions, but the neurobiological mechanisms underlying such putative effects...
DOI: 10.1017/neu.2026.10059 (opens in new tab)
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Neuroplasticity
Remyelination
Neuroprotection
Central nervous system
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