Demyelination, defined as the loss of myelin sheaths around neuronal axons, is increasingly recognized as a key factor in a broad range of psychiatric and neurological disorders, including schizophrenia, major depressive disorder, bipolar disorder, post-traumatic stress disorder, autism spectrum disorder, substance use disorders, Alzheimer's disease, Parkinson's disease, and multiple sclerosis....
S ummary In 45 normal subjects changes in the horizontal eye movements following the administration of psychotropic drugs have been studied. 1. Following the administration of amobarbital (250 mg, i.v.) and chlorpromazine (1.0mg/kg, i.m.), rapid eye movements (R) decreased gradually until they disappeared altogether. 2. LSD 25 (0.5 or 1.0γ/kg, i.m.) produced increase of R in 80% and markedly...