Actions of Mescaline on Isolated Rat Atria
Journal of Pharmaceutical Sciences July 1, 1977 Peter K. S. Siegl, Raymond F. Orzechowski 2 citations
Mescaline, in concentrations of 5 x 10(-4) and 1 x 10(-3) M, produced negative chronotropic and positive inotropic responses in isolated, spontaneously beating rat atria. In tissues driven at a constant rate, the inotropic response was diminished greatly, indicating that the increment in the force of contraction was secondary to the reduction in rate. These chronotropic and inotropic responses...