3,4-Methylenedioxymethamphetamine (Ecstasy) Inhibits Dyskinesia Expression and Normalizes Motor Activity in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Primates
Journal of Neuroscience October 8, 2003 Mahmoud M. Iravani, Michael S. Jackson, Mikko Kuoppamäki et al. 105 citations
Ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] was shown to prolong the action of l -3,4-dihydroxyphenylalanine ( l -DOPA) while suppressing dyskinesia in a single patient with Parkinson's disease (PD). The clinical basis of this effect of MDMA is unknown but may relate to its actions on either dopaminergic or serotoninergic systems in brain. In normal, drug-naive common marmosets, MDMA...