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A Braun

2 papers in the library · 32 citations · publishing 2011-2013

Papers

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Cognitive impairments from developmental exposure to serotonergic drugs: citalopram and MDMA

The International Journal of Neuropsychopharmacology January 11, 2013 Tori L. Schaefer, Curtis E. Grace, A Braun et al. 24 citations

Abstract We previously showed that developmental 3,4-methylenedioxymethamphetamine (MDMA) treatment induces long-term spatial and egocentric learning and memory deficits and serotonin (5-HT) reductions. During brain development, 5-HT is a neurotrophic factor influencing neurogenesis, synaptogenesis, migration, and target field organization. MDMA (10 mg/kg × 4/d at 2 h intervals) given on...

Distinct periods of developmental sensitivity to the effects of 3,4-(±)-methylenedioxymethamphetamine (MDMA) on behaviour and monoamines in rats

The International Journal of Neuropsychopharmacology June 28, 2011 Matthew R. Skelton, Devon L. Graham, Tori L. Schaefer et al. 8 citations

Previous findings showed allocentric and egocentric learning deficits in rats after MDMA treatment from postnatal days (PD) 11-20 but not after treatment from PD 1-10. Shorter treatment periods (PD 1-5, 6-10, 11-15, or 16-20) resulted in allocentric learning deficits averaged across intervals but not for any interval individually and no egocentric learning deficits individually or collectively....