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Howard H. Gu

1 paper in the library · 419 citations · publishing 2006

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Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs

BMC Pharmacology March 3, 2006 Dawn D. Han, Howard H. Gu 419 citations

Abstract Background The plasma membrane neurotransmitter transporters terminate neurotransmissions by the reuptake of the released neurotransmitters. The transporters for the monoamines dopamine, norepinephrine, and serotonin (DAT, NET, and SERT) are targets for several popular psychostimulant drugs of abuse. The potencies of the psychostimulant on the monoamine transporters have been studied...