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Mark S. Michaels

1 paper in the library · 39 citations · publishing 2008

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Cardiac effects of MDMA on the metabolic profile determined with 1H‐magnetic resonance spectroscopy in the rat

NMR in Biomedicine November 4, 2008 Shane A. Perrine, Mark S. Michaels, Farhad Ghoddoussi et al. 39 citations

Abstract Despite the potential for deleterious (even fatal) effects on cardiac physiology, 3,4‐methylenedioxymethamphetamine (MDMA; ecstasy) abuse abounds driven mainly by its euphoric effects. Acute exposure to MDMA has profound cardiovascular effects on blood pressure and heart rate in humans and animals. To determine the effects of MDMA on cardiac metabolites in rats, MDMA (0, 5, or 10...