The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA
Journal of Psychopharmacology January 24, 2011 Jéssica Ruiz‐medina, Catherine Ledent, Olga Carretón et al. 33 citations
Adenosine is an endogenous purine nucleoside that plays a neuromodulatory role in the central nervous system. A2a adenosine receptors have been involved in reward-related processes, inflammatory phenomena and neurotoxicity reactions. In the present study, we investigated the role of A2a adenosine receptors on the acute pharmacological effects, reinforcement and neuroinflammation induced by MDMA...