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Alan O'Donohoe

2 papers in the library · 137 citations · publishing 1998-2000

Papers

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Agony and ecstasy: a review of MDMA effects and toxicity

European Psychiatry August 1, 2000 C. Burgess, Alan O'Donohoe, Michael Gill 108 citations

Summary Background Background – Ecstasy is a recreational drug with an anecdotal reputation for safety. However, reports of adverse effects and fatalities have increased in the medical and popular press. Methods Method – Literature search and review. Results Results – Acute Ecstasy toxicity does not appear to be due to overdose and cannot be solely attributed to the nature of the usual ambient...

MDMA toxicity: no evidence for a major influence of metabolic genotype at CYP2D6

Addiction Biology July 1, 1998 Alan O'Donohoe, Karen O’flynn, Kevin Shields et al. 29 citations

Abstract 3,4 Methylenedioxymethamphetamine (MDMA or ecstasy) has become a major drug of abuse over the last decade. It produces a mixture of systemic and neuropsychological effects. Animal studies show a range of short‐ and long‐term toxic effects, both systemically and neurochemically. In humans, toxicity and death due to the drug have been attributed to a variety of causes, with...