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H. S. Fischer

1 paper in the library · 54 citations · publishing 2000

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MDMA (‘ecstasy’) enhances basal acetylcholine release in brain slices of the rat striatum

European Journal of Neuroscience April 1, 2000 H. S. Fischer, Gerald Zernig, Dieter S. Schatz et al. 54 citations

Abstract The pharmacological basis of acute (±)‐MDMA (3,4‐methylenedioxymethamphetamine) intoxication still awaits full characterization. According to present knowledge, MDMA enhances the release of serotonin and dopamine in striatal slices and interacts with different types of receptors such as 5‐HT 2 (5‐hydroxytryptamine or serotonin), M 1 and M 2 muscarinic acetylcholine (ACh), and histamine...