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Dhwanil Shah

1 paper in the library · 54 citations · publishing 2002

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Action of MDMA (Ecstasy) and Its Metabolites on Arginine Vasopressin Release

Annals of the New York Academy of Sciences June 1, 2002 John K. Fallon, Dhwanil Shah, Andrew T. Kicman et al. 54 citations

A bstract : 3,4‐Methylenedioxymethamphetamine (MDMA) has been reported to cause hyponatraemia, which appears to result from inappropriate secretion of the antidiuretic hormone arginine vasopressin (AVP). After administration of a low dose of ( R,S )‐MDMA (40 mg) to eight healthy drug‐free male volunteers, concentrations of AVP in plasma increased significantly at 1, 2, and 4 hours. Although no...