Investigation of serotonin-1A receptor function in the human psychopharmacology of MDMA
Journal of Psychopharmacology July 17, 2008 Felix Hasler, Erich Studerus, Karl‐johan Lindner et al. 53 citations
Serotonin (5-HT) release is the primary pharmacological mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) action in the primate brain. Dopamine release and direct stimulation of dopamine D2 and serotonin 5-HT 2A receptors also contributes to the overall action of MDMA. The role of 5-HT 1A receptors in the human psychopharmacology of MDMA, however, has not yet been elucidated. In...