Abstract Simultaneous determination of 3,4‐methylenedioxymethamphetamine (MDMA) and 3,4‐methylenedioxyamphetamine (MDA) in rat blood and brain microdialysates by high‐performance liquid chromatography with fluorescence detection (HPLC‐FL) was developed. Microdialysates were directly subjected to derivatization with 4‐(4,5‐diphenyl‐1 H ‐imidazol‐2‐yl)benzoyl chloride (DIB‐Cl). The...
Abstract A sensitive semi‐micro column high‐performance liquid chromatography with fluorescence detection method was developed for the determination of 3,4‐methylenedioxymethamphetamine (MDMA), 3,4‐methylenedioxyamphetamine (MDA), methamphetamine (MP) and amphetamine (AP) in human hair. 4‐(4,5‐Diphenyl‐1 H ‐imidazol‐2‐yl)benzoyl chloride (DIB‐Cl) and 1‐methyl‐3‐phenylpropylamine were used as...
Abstract A simultaneous semi‐micro column HPLC method with fluorescence detection of abused drugs, such as 3,4‐methylenedioxymethamphetamine (MDMA), 3,4‐methylenedioxyamphetamine (MDA), amphetamine (AP) and methamphetamine (MP) in rat urine was examined by using 4‐( N , N ‐dimethylaminosulphonyl)‐7‐fluoro‐1,2,3‐benzoxadiazole (DBD‐F) as a labelling reagent and α ‐phenylethylamine as an internal...