In vivo detection of short- and long-term MDMA neurotoxicity?a positron emission tomography study in the living baboon brain
Synapse June 1, 1998 Ursula Scheffel, Zsolt Szabó, William B. Mathews et al. 146 citations
The present study evaluated short- and long-term effects of MDMA (3,4-methylenedioxymethamphetamine) in the baboon brain using PET and [11C](+)McN 5652, a potent 5-HT transporter ligand, as well as [11C]RTI-55, a cocaine derivative which labels both 5-HT and dopamine transporters. Following baseline PET scans with [11C](+)McN5652, [11C](-)McN5652 (the inactive enantiomer of the active...