J Wlos

2 papers in the library · 269 citations · publishing 1993-1995

Papers

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Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")

Journal of Neuroscience August 1, 1995 Christina Weide Fischer, George Hatzidimitriou, J Wlos et al. 269 citations

The recreational drug (+/)3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) is a methamphetamine derivative that selectively destroys central 5-HT axons and axon terminals in animals and, possibly, humans. The fate of 5-HT neurons following MDMA injury is uncertain. In particular, while it is known that central 5-HT axons can undergo regenerative sprouting after MDMA injury, it has not been...

DOI: 10.1523/jneurosci.15-08-05476.1995 Full text MDMA Ecstasy Recreational drug Hallucinogen +2

3,4-Methylenedioxymethamphetamine, serotonin and memory.

Journal of Pharmacology and Experimental Therapeutics August 1, 1993 George A. Ricaurte, A L Markowska, G L Wenk et al.

The recreational drug (+/-)-3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") is toxic to central serotonin (5-HT) neurons, but few long-term functional consequences of MDMA neurotoxicity have been identified. Because 5-HT has been implicated in learning and memory, the present study was undertaken to examine whether MDMA, by damaging 5-HT neurons, altered mnemonic function on a long-term...

DOI: 10.1016/s0022-3565(25)38362-x Serotonin Animals Rats N-methyl-3,4-methylenedioxyamphetamine +8