Ketamine Increases Human Motor Cortex Excitability to Transcranial Magnetic Stimulation
The Journal of Physiology March 1, 2003 Vincenzo Di Lazzaro, Antonio Oliviero, Paolo Profice et al. 255 citations
Subanaesthetic doses of the N ‐methyl‐ d ‐aspartate (NMDA) antagonist ketamine have been shown to determine a dual modulating effect on glutamatergic transmission in experimental animals, blocking NMDA receptor activity and enhancing non‐NMDA transmission through an increase in the release of endogenous glutamate. Little is known about the effects of ketamine on the excitability of the human...