ISSN 1469-7793
4 papers in the library · 256 citations · publishing 2003-2026
The Journal of Physiology July 7, 2026 Elifrances Galdino de Oliveira
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The Journal of Physiology June 1, 2026 Felipe Guiffa-Gómez, Sashá Van Buuren, Freddy Aguilar et al. 1 citation
The medial prefrontal cortex (mPFC) undergoes extensive GABAergic interneuron maturation during adolescence, a process that establishes excitatory-inhibitory balance and supports adult cognitive function. Disruptions during this critical developmental period contribute to neuropsychiatric disorders, yet the enduring consequences for adult synaptic plasticity remain poorly understood. Here we...
The Journal of Physiology October 1, 2024 Jesús Pardo-Valencia, Miryam Moreno-Gomez, Noelia Mercado et al.
Consciousness, defined as being aware of and responsive to one's surroundings, is characteristic of normal waking life and typically is lost during sleep and general anaesthesia. The traditional view of consciousness as a global brain state has evolved toward a more sophisticated interplay between global and local states, with the presence of local sleep in the awake brain and local wakefulness...
The Journal of Physiology March 1, 2003 Vincenzo Di Lazzaro, Antonio Oliviero, Paolo Profice et al. 255 citations
Subanaesthetic doses of the N ‐methyl‐ d ‐aspartate (NMDA) antagonist ketamine have been shown to determine a dual modulating effect on glutamatergic transmission in experimental animals, blocking NMDA receptor activity and enhancing non‐NMDA transmission through an increase in the release of endogenous glutamate. Little is known about the effects of ketamine on the excitability of the human...