Therapeutic Properties of Ayahuasca Components in Ischemia/Reperfusion Injury of the Eye
Biomedicines April 26, 2022 Anna Szilágyi, Barbara Takács, Réka Szekeres et al. 10 citations
Ischemic eye diseases are major causes of vision impairment. Thus, potential retinoprotective effects of N’N-dimethyltryptamine (DMT) were investigated. To inhibit its rapid breakdown by monoamine-oxidase A (MAO-A) enzyme, DMT was co-administered with harmaline, a β-carboline in the Amazonian Ayahuasca brew. Using ligation, 60 min of ischemia was provoked in eyes of rats, followed by 7 days of...