Effects of chronic administration of antidepressant drugs on central serotonergic receptor mechanisms
Palgrave Macmillan UK eBooks 1983 Sven Ove Ögren, Kjell Fuxé, Odd‐geir Berge et al. 11 citations
The present studies have shown that chronic antidepressant treatment with desipramine (DMI), imipramine (IMI) and zimelidine produced behavioral evidence for sub- and supersensitivity depending on 5-HT agonist dose and types of behavior examined. Thus, chronic treatment with all three drugs reduced head twitches induced by a high dose of the 5-HT agonist 5-methoxy-N,N-dimethyltryptamine...