Enhancing action of LSD on neuronal responsiveness to serotonin in a brain structure involved in obsessive–compulsive disorder
The International Journal of Neuropsychopharmacology March 1, 2003 Tarek Zghoul, Pierre Blier 13 citations
Potent serotonin (5-HT) reuptake inhibitors are the only drugs that consistently exert a therapeutic action in obsessive-compulsive disorder (OCD). Given that some hallucinogens were reported to exert an anti-OCD effect outlasting their psychotomimetic action, possible modifications of neuronal responsiveness to 5-HT by LSD were examined in two rat brain structures: one associated with OCD, the...
DOI: 10.1017/s1461145702003218 (opens in new tab)
Serotonin
Hippocampus
Hallucinogen
Inhibitory postsynaptic potential
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