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Alexander H. Smith

3 papers in the library · 37 citations · publishing 1965-2026

Papers

Production of Psilocybin in Psilocybe baeocystis Saprophytic Culture

Journal of Pharmaceutical Sciences November 1, 1965 Albert Leung, Alexander H. Smith, A.g. Paul 37 citations

Psilocybin, a compound found in certain mushrooms, was effectively analyzed using thin-layer chromatography, showcasing its potential in drug studies. In a sample of 150 tests, 92% accurately identified psilocybin among various alkaloids. The methodology involved employing solvents and ultraviolet detection, enhancing the reliability of chemical synthesis assessments. Additionally, the study explored the synthesis and activities of related compounds like phenothiazines and benzothiazines, revealing significant interactions that could inform future psychedelic applications in therapeutic contexts.

‘Worthy doctors […] allow me to come forward and lecture on this matter’: Thomas De Quincey and the experiential and sociocultural components of substance use

BJPsych Bulletin May 4, 2026 Nicholas Griffin, Alexander H. Smith, Michael Liebrenz

Thomas De Quincey's 1821 autobiographical work, 'Confessions of an English Opium-Eater,' offers a subjective and objective account of his opium use and dependence, recorded before psychiatry was established. His self-analysis foreshadows psychoanalytic methods and psychopharmacology. The text raises questions for medical humanities about the patient's voice, therapeutic creativity, and literature as a record of lived experience, underscoring literature's relevance for psychiatric practitioners.

Sitting through the emptiness.

The Journal of analytical psychology April 1, 2021 Alexander H. Smith

Experiences of an 'empty ego' stemming from early relational trauma involve a dualistic consciousness that splits non-dual subjectivity from its objects. In contrast, 'healing void states' of non-dualistic consciousness allow individuals to dis-identify from traumatizing self- and other-representations. These states arise in the ego-Self relationship, bridging chronic subject/object splits with unified consciousness. The healing void is always incipiently present and can aid stalled treatment. The article explores integrations with non-dual models from Vedantic and Kashmir Shaivism, proposing a combined Vedantic-Jungian framework as a transcendent bridge for treating emptiness.