In vivo production of psilocybin in E. coli
Metabolic Engineering September 21, 2019 Alexandra M. Adams, Nicholas A. Kaplan, Zhangyue Wei et al. 83 citations
Psilocybin, the prodrug of the psychoactive molecule psilocin, has demonstrated promising results in clinical trials for the treatment of addiction, depression, and post-traumatic stress disorder. The development of a psilocybin production platform in a highly engineerable microbe could lead to rapid advances towards the bioproduction of psilocybin for use in ongoing clinical trials. Here, we...