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Pierre-Jean Ferron

2 papers in the library · 54 citations · publishing 2022

Papers

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Metabolite elucidation of 2-fluoro-deschloroketamine (2F-DCK) using molecular networking across three complementary in vitro and in vivo models.

Drug Testing and Analysis 2022 Thomas Gicquel, Romain Pelletier, Camille Richeval et al. 32 citations

This work first aims to investigate metabolites of 2-fluoro-deschloroketamine (2F-DCK), a new arylcyclohexylamine derivatives (a group of dissociative ketamine-based substances) using two in vitro experimental approaches, and to compare obtained results by means of molecular networking. Metabolites of 2F-DCK were investigated using both human liver microsomes (HLMs) and hepatic (HepaRG) cell...

New psychoactive substance cocktail in an intensive care intoxication case elucidated by molecular networking.

Clinical toxicology (Philadelphia, Pa.) 2022 Romain Pelletier, Brendan Le Daré, Loic Grandin et al. 22 citations

The recreational use of new psychoactive substances (NPS) is increasing worldwide. Among them, the arylcyclohexylamine family including phencyclidine (PCP) and ketamine derivatives is increasing. We report a non-fatal intoxication mainly due to arylcyclohexylamine compounds illustrated by molecular networking (MN). A 37-year-old man with a history of drug abuse was discovered with several bags...