Ayahuasca and its major component harmine promote antinociceptive effects in mouse models of acute and chronic pain.
Journal of Ethnopharmacology April 6, 2024 Pedro Santana Sales Lauria, Juliana de Medeiros Gomes, Lucas Silva Abreu et al. 10 citations
Ayahuasca (AYA) is a psychedelic brew used in religious ceremonies. It is broadly used as a sacred medicine for treating several ailments, including pain of various origins. To investigate the antinociceptive effects of AYA and its mechanisms in preclinical models of acute and chronic pain in mice, in particular during experimental neuropathy. The antinociceptive effects of AYA administered...