Caoimhe M. Coyle

The use of ketamine as an antidepressant: a systematic review and meta‐analysis

Human Psychopharmacology: Clinical and Experimental April 7, 2015 Caoimhe M. Coyle, Keith R. Laws 279 citations

Objective The current meta‐analysis examines the effects of ketamine infusion on depressive symptoms over time in major depressive disorder (MDD) and bipolar disorder (BD). Methods Following a systematic review of the literature, data were extracted from 21 studies ( n = 437 receiving ketamine) and analysed at four post‐infusion time points (4 h, 24 h, 7 days and 12–14 days). The moderating...