Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-Hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex
Journal of Neuroscience October 1, 2003 Javier González-Maeso, Tony Yuen, Barbara J. Ebersole et al. 295 citations
Most neuropharmacological agents and many drugs of abuse modulate the activity of heptahelical G-protein-coupled receptors. Although the effects of these ligands result from changes in cellular signaling, their neurobehavioral activity may not correlate with results of in vitro signal transduction assays. 5-Hydroxytryptamine 2A receptor (5-HT2AR) partial agonists that have similar...
DOI: 10.1523/jneurosci.23-26-08836.2003 (opens in new tab)
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Lysergic acid diethylamide
Signal transduction
Transcriptome
Receptor
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