Mini-review: The neurobiology of treating substance use disorders with classical psychedelics
Frontiers in Neuroscience April 17, 2023 Marvin M. Urban, Moritz R. Stingl, Marcus W. Meinhardt 47 citations
The potential of psychedelics to persistently treat substance use disorders is known since the 1960s. However, the biological mechanisms responsible for their therapeutic effects have not yet been fully elucidated. While it is known that serotonergic hallucinogens induce changes in gene expression and neuroplasticity, particularly in prefrontal regions, theories on how specifically this...