A systematic review of 13 studies found that classic serotonergic psychedelics (psilocybin, LSD, DMT, ayahuasca) are associated with increases in mindfulness, particularly in acceptance-related domains such as non-judgement of inner experience and non-reactivity. A meta-analysis of 6 studies showed small overall effects from ayahuasca ingestion on mindfulness facets including non-judgement, non-reactivity, and acting with awareness. The authors note substantial variability across studies in participants, psychedelic administration, and mindfulness measurement, and call for more methodologically robust research to clarify the relationship.
A systematic review of 13 studies found that ingesting classic serotonergic psychedelics such as psilocybin, LSD, DMT, and ayahuasca is associated with increases in mindfulness, particularly in the domains of acceptance, non-judgement of inner experience, and non-reactivity. A meta-analysis of 6 studies showed small overall effects from ayahuasca ingestion, increasing mindfulness facets of non-judgement, non-reactivity, and acting with awareness. The review notes substantial variability across studies in participant characteristics, psychedelic administration, and mindfulness measurement, and calls for further methodologically robust research to clarify the relationship.