Experimental strategies to discover and develop the next generation of psychedelics and entactogens as medicines
Neuropharmacology December 15, 2022 David J Heal, Jane Gosden, Sharon L. Smith et al. 18 citations
Research on classical psychedelics (psilocybin, LSD and DMT) and entactogen, MDMA, has produced a renaissance in the search for more effective drugs to treat psychiatric, neurological and various peripheral disorders. Psychedelics and entactogens act though interaction with 5-HT2A and other serotonergic receptors and/or monoamine reuptake transporters. 5-HT, which serves as a neurotransmitter...