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Aisling Spain

1 paper in the library · 45 citations · publishing 2015

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Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brain

Neuropharmacology July 18, 2015 Aisling Spain, Clare Howarth, Alexandre A. Khrapitchev et al. 45 citations

The development of pharmacological magnetic resonance imaging (phMRI) has presented the opportunity for investigation of the neurophysiological effects of drugs in vivo. Psilocin, a hallucinogen metabolised from psilocybin, was recently reported to evoke brain region-specific, phMRI signal changes in humans. The present study investigated the effects of psilocin in a rat model using phMRI and...