A Handbook on Drug and Alcohol Abuse
June 3, 2004
Gail Winger, James H Woods, Frederick G Hofmann
Abstract Club drugs are typically taken by groups of people during raves. Raves are parties where the opportunity to dance to very loud, rhythmic music while under the influence of one or more drugs is the primary attraction. Needless to say, most users of club drugs under these conditions are young and single. Club drugs are usually taken periodically; several of them may be taken three to...
Behavioural Pharmacology
March 1, 2004
William E Fantegrossi, James H Woods, Gail Winger
99 citations
Relatively few studies have assessed the reinforcing effects of hallucinogenic compounds, and no such studies have attempted to engender contingent responding for these compounds in animals with behavioral histories that include experience with serotonergically mediated reinforcing effects. The objectives of the present study were to investigate the capacity of several hallucinogenic compounds...
Journal of Pharmacology and Experimental Therapeutics
June 1, 1988
W. Koek, James H Woods, Gail Winger
The behavioral effects of MK-801 [(+)-5-methyl-10,11-dihydroxy-5H-dibenzo(a,d)cyclohepten-5,10-imin e], a proposed noncompetitive N-methyl-D-aspartate (NMDA) antagonist, were compared to those of phencyclidine (PCP). In pigeons, MK-801 produced PCP-like catalepsy (i.e., loss of righting without eye closure and without muscle relaxation) and PCP-like discriminative stimulus effects. In rats,...
Journal of Pharmacology and Experimental Therapeutics
October 1, 1987
A. E. Jacobson, E. A. Harrison, M. V. Mattson et al.
Dioxadrol exists in four isomeric forms. alpha-(+)-Dioxadrol (dexoxadrol) showed phencyclidine (PCP)-like activity in rhesus monkeys trained to discriminate s.c. administration of ketamine, but neither alpha-(-)-dioxadrol (levoxadrol) nor beta-(+/-)-dioxadrol showed such activity. In addition, response-contingent i.v. dexoxadrol maintained higher rates of responding than either levoxadrol or...