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William J. Panenka

3 papers in the library · 22 citations · publishing 2020-2024

Papers

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A scoping review of the effects of mushroom and fungus extracts in rodent models of depression and tests of antidepressant activity

Frontiers in Pharmacology June 3, 2024 Gio Kim, Catherine K. Wang, Lily R. Aleksandrova et al. 3 citations

One of the most important developments in psychopharmacology in the past decade has been the emergence of novel treatments for mood disorders, such as psilocybin for treatment-resistant depression. Psilocybin is most commonly found in different species of mushroom; however, the literature on mushroom and fungus extracts with potential antidepressant activity extends well beyond just...

Chronic Treatment With Psilocybin Decreases Changes in Body Weight in a Rodent Model of Obesity

Frontiers in Psychiatry May 18, 2022 Joyce Huang, Michelle Pham, William J. Panenka et al. 19 citations

Background There are currently relatively few effective pharmacological treatments for obesity, and existing ones may be associated with limiting side-effects. In the search for novel anti-obesity agents, drugs that modify central serotonergic systems have historically proven to be effective in promoting weight loss. Psilocin, which is rapidly metabolized from psilocybin, is an agonist at...

Differential effects of cannabis exposure during early versus later adolescence on the expression of psychosis in homeless and precariously housed adults.

Progress in Neuro-Psychopharmacology and Biological Psychiatry September 2, 2020 K. Gicas, Alex Y T Cheng, William J. Panenka et al.

Longitudinal studies of cannabis exposure during early adolescence in the general population frequently report an increased risk of subsequently developing psychotic symptoms or a psychotic illness. However, there is a dearth of knowledge about the effects of early cannabis exposure on psychosis in homeless and precariously housed adults, who represent a population afflicted with high rates of...