Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat
Acta Neuropsychiatrica May 20, 2019 Oskar Hougaard Jefsen, Kristoffer Højgaard, Sofie Laage Christiansen et al. 66 citations
Abstract Objective: Psilocybin is a serotonin receptor agonist with a therapeutic potential for treatment-resistant depression and other psychiatric illnesses. We investigated whether the administration of psilocybin had an antidepressant-like effect in a rat model of depression. Methods: Using the Flinders Sensitive Line (FSL) rat model of depression, we assessed the antidepressant-like effect...