Psilocybin restrains activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms
Molecular Psychiatry April 27, 2024 Kyna Conn, L K Milton, K Huang et al. 44 citations
Abstract Psilocybin has shown promise for alleviating symptoms of depression and is currently in clinical trials for the treatment of anorexia nervosa (AN), a condition that is characterised by persistent cognitive inflexibility. Considering that enhanced cognitive flexibility after psilocybin treatment is reported to occur in individuals with depression, it is plausible that psilocybin could...
DOI: 10.1038/s41380-024-02575-9 (opens in new tab)
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Eating disorders
Psilocybin therapy
Cognitive flexibility
Animal research