Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder.
Translational Psychiatry November 8, 2021 Manoj K. Doss, Michal Považan, Monica D Rosenberg et al. 343 citations
Psilocybin has shown promise for the treatment of mood disorders, which are often accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have proposed neuropsychoplastogenic effects as mechanisms underlying the enduring therapeutic effects of psilocybin. In an open-label study of 24 patients with major depressive disorder, we tested the enduring effects of psilocybin...