Romain Bordy

Psilocybin reduces alcohol self-administration via selective left nucleus accumbens activation in rats

Brain May 4, 2024 Jérôme Jeanblanc, Romain Bordy, Grégory Fouquet et al. 10 citations

Abstract The use of psilocybin to treat alcohol use disorder is very promising, but its mechanisms of action remain poorly understood. We combined behavioural, pharmacological and gene expression analyses to decipher the mechanisms of action of psilocybin, for the first time, when injected into the brain. Male Long Evans rats underwent chronic operant ethanol self-administration before testing...