Esketamine attenuates post-traumatic stress disorder via suppressing neuroinflammation and abnormal myelination.
Neurochemistry International November 19, 2025 Zhaoliang Gu, Ruixue Song, Guoqiang Liu et al. 3 citations
Post-traumatic stress disorder (PTSD) is a chronic psychological disorder that is induced by traumatic events. The pathophysiological mechanism of PTSD involves complex neurobiological processes. However, the underlying mechanism is not clear, leading to lack of effective therapeutic interventions. Mice were exposed to the electric foot shocks using the contextual fear memory paradigm. A...