Classics in Chemical Neuroscience: Muscimol.
ACS Chemical Neuroscience September 18, 2024 Diego Rivera-Illanes, Gonzalo Recabarren-Gajardo 17 citations
Muscimol (3) is a psychoactive isoxazole present in various Amanita mushrooms, along with ibotenic acid and muscarine. It is structurally related to GABA and acts as a GABAA agonist with great affinity. Muscimol use dates back to Siberian shamanic cultures as an entheogen, where it was ingested orally to exert psychoactive effects. Although not approved for clinical use, its potential and use...